Do you struggle with depression and memory problems?
Why you should join
Living with Major Depressive Disorder and Brain Fog
When you're depressed, it can feel like you don't get anything right. Things like brain fog, or forgetting your keys can send you in a downward spiral. Depression and brain fog are more than just hormones or having a bad day and without help, they can be impossible to shake.
What is this trial about?
This trial is investigating whether using a drug called Xanamem® can decrease cortisol levels in the brain. Cortisol is a steroid hormone produced by the adrenal glands and chronically high levels are associated with depression and memory problems. Xanamem is a registered trademark of Actinogen Medical Limited.
What are the Benefits of Joining?
By joining this trial you'll have a positive impact on helping science find better ways to fight brain fog and depression. Things like your travel to the site will be paid for, and we can even organise this for you. You'll also have access to close medical monitoring and a team that really care.
About Us
Goals
The aim of this study is to test how well Xanamem helps to reduce symptoms of brain fog and depression. It does this by reducing the amount of a hormone called cortisol in the body. High levels of cortisol are associated with memory problems and depression.
We're hoping to improve depression and memory problems like frequent forgetfulness, difficulty making decisions and a lack of the brain's ability to adapt to new, changing or unplanned events.
Goals
The aim of this study is to test how well Xanamem helps to reduce symptoms of brain fog and depression. It does this by reducing the amount of a hormone called cortisol in the body. High levels of cortisol are associated with memory problems and depression.
We're hoping to improve depression and memory problems like frequent forgetfulness, difficulty making decisions and a lack of the brain's ability to adapt to new, changing or unplanned events.
Process
After signing up and being deemed eligible, someone will call you with more information about the trial. The trial is a maximum of 14 weeks, it consists of a Screening period (at most 4 weeks), treatment period (6 weeks), and a follow-up period (4 weeks).
During the study there is 6-7 visits to the site you must complete which are roughly 2 weeks apart, however you can pick the site closest to you and we can organise and pay for your transport.
You'll need to take a pill each morning which will either be Xanamem or a placebo (a pill without any medicine). We won't know which one you're getting, and neither will you. This is to make sure the results are fair and accurate.
Industry Experience
Actinogen
Actinogen Medical (ACW) is a pioneering biotechnology company dedicated to advancing a cutting-edge therapy targeting neurological disorders linked to imbalanced brain cortisol levels. Their lead compound, Xanamem, is designed to address conditions such as Alzheimer’s Disease and Major Depressive Disorder. Actinogen are committed to reshaping the landscape of neurological care and improving patients' lives.
Requirements
for participants
You'll need to have brain fog symptoms like slowness of thinking, difficulty making decisions, having trouble keeping focused and forgetfulness.
Do you have an ongoing depressed mood, diminished interest in activities, feelings of worthlessness, guilt, fatigue, and changes in weight or appetite.
While most medications commonly prescribed for depression are allowed, you can't be taking St John's wort, oral corticosteroids (synthetic hormones) or drugs that can cause damage to the peripheral nerves.
What we are looking for
Sex assigned at birth
All
Age
18 Years to 75 Years
Trial Locations
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